Description
Product Characteristics:
Aliases: ARHG8_HUMAN antibody, ARHGEF8 antibody, GLYT2 antibody, Guanine nucleotide regulatory protein oncogene antibody, MGC114559 antibody, MGC127767 antibody, MGC53602 antibody, mNET1 antibody, Net1 antibody, NET1A antibody, Neuroepithelial cell transforming gene 1 antibody, Neuroepithelial cell-transforming gene 1 protein antibody, p65 Net1 proto oncogene antibody, Proto-oncogene p65 Net1 antibody, Rho guanine nucleotide exchange factor 8 antibody, Rho guanine nucleotide exchange factor GEF 8 antibody
Target Information: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]