Description
Product Characteristics: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.,C16orf8,Dist1,EGFR-RS,gene-89,gene-90,hDist1,RHBDF1,Signal Transduction,RHBDF1
Target Information: Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)