Description
Product Characteristics:
Aliases: CDC25 antibody, CDC25L antibody, GNRP antibody, GRF1 antibody, GRF55 antibody, Guanine nucleotide exchange factor antibody, Guanine nucleotide releasing factor 55 kD antibody, Guanine nucleotide releasing protein antibody, guanine nucleotide-releasing factor 1 antibody, Guanine nucleotide-releasing protein antibody, H GRF55 antibody, HGRF55 antibody, PP13187 antibody, Ras protein specific guanine nucleotide releasing factor 1 antibody, Ras specific guanine nucleotide releasing factor antibody, Ras specific guanine nucleotide releasing factor CDC25 homolog antibody, Ras specific nucleotide exchange factor CDC25 antibody, Ras-GRF1 antibody, Ras-specific guanine nucleotide-releasing factor 1 antibody, Ras-specific nucleotide exchange factor CDC25 antibody, RASGRF1 antibody, RGRF1_HUMAN antibody
Target Information: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]