Description
Product Characteristics:
Aliases: GAP1 like protein antibody, MRASAL antibody, RAS GTPase activating protein like antibody, RAS protein activator like 1 (GAP1 like) antibody, RAS protein activator like 1 antibody, RASAL antibody, Rasal1 antibody, rasGAP activating like protein 1 antibody, RasGAP-activating-like protein 1 antibody, RASGAP1 LIKE antibody, RASL1_HUMAN antibody
Target Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]