Fig 1: miR-200b/c decreases proliferation and migration of ovarian cancer cells via mortalin. After transfection of A2780S and A2780CP cells with miR-200b/c mimic or NC, (A) cell viability was determined using the CCK-8 assay. (B) Representative images from the wound healing assay of different groups at 0 and 48 h (scale bar, 50 μm). Quantification of the wound-healing area. (C) Migration of ovarian cancer cells was determined via transwell assay (scale bar, 20 μm). Average cell counts of 10 randomly selected fields. (D) Protein levels of Erk1/2, p-Erk1/2, Akt, and p-Akt were determined via Western blotting. Biological replication (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001.