Human IgG1 kappa, Isotype Control HY-P99001 from MedChemExpress

Product Specs
ItemHuman IgG1 kappa, Isotype Control
CompanyMedChemExpress
Price $300.00Supplier Page View Company Product Page
Catalog NumberHY-P99001
Quantity1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeChemical
Purity99.71%
Research AreaInflammation/Immunology; Cancer
Molecule NameHuman IgG1 kappa, Isotype Control

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(1) EBV infection outcomes determined by monocyte and TREG-driven immune dynamics in an ex vivo pbmc modelPLoS PathogMarch 20, 2026Leena Yoon, Lauren N. MacMullen, Leonardo Josué Castro Muñoz, Alina Gu, Jamie Bregman, Mary S. Campion, Avi Srivastava, Rena R. Xian, Richard F. Ambinder, Andrew Kossenkov, et al.cell culture medium [58]. An equivalent concentration of human IgG1 isotype control (MedChemExpress, Cat# HY-P99001) was used in control conditions (Mock and EBV). Cells were then infected with the MUTU1 strain of EBV

(2) Beyond CD30: Dual‐Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis FungoidesAdvanced ScienceFebruary 28, 2026Yi Jiang, Pan Lai, Mingjia Li, Yujie Wen, Mengzhou Cao, Yu Xiao, Zhuojing Chen, Jingru Sun, Yang Wangsame components as BV, whereas the monoclonal antibody targeting CD30 is replaced by human IgG1 kappa (HY‐P99001) that does not bind to the target. BCL2 inhibitors, including venetoclax (HY‐15531) and navitoclax (HY‐10087)

(3) pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic ImmunotherapyAdvanced ScienceFebruary 13, 2026Huan Li, Yun Li, Yating Hu, Yanbing Yao, Yaodong He, Jing Li, Jiaqi Tang, Zhenyan Zhao, Yan Wang, Yulun He, et al.administered every 2 days). Isotype control experiments used hydrogels loaded with Human IgG1 kappa (#HY‐P99001, MCE) at the same loading concentration as Enoblituzumab. Subcutaneously injecting OSCC cells (CAL‐27,

(4) M6A modification-related genes characterize prognostic risk and immune regulation in lung adenocarcinomaBMC CancerJanuary 16, 2026Xiaoxing Liu, Shanshan Li, Min Zhou, Ning Ding, Jinzhong Chen, Ning Zhouanti-MIF neutralizing antibody (MedChemExpress, HY-P99262) or isotype control IgG (MedChemExpress, HY-P99001) for 24 h. Cells were then lysed in ice-cold RIPA buffer (Beyotime) supplemented with PMSF and protease/phosphatase

(5) TREM1 facilitates nonresponse to anti-TNF-α monoclonal antibodies in colitis via boosting ITCH/TAK1/caspase-8 axis-mediated macrophage pyroptosisJournal of Translational MedicineNovember 18, 2025Xiao-Man Liu, Zhen-Zhen Dai, Shang-Jian Luo, Jin-Yang Zhai, Yang Xie, Ying-Wei Chenestablish an acute colitis model. IFX (10 µg/g, HY-P9970, MCE) or control human IgG1 antibody (10 µg/g, HY-P99001, MCE) was injected via the tail vein for treatment. Three cycles of DSS administration (7 days of 3%

(6) High-throughput single-cell analysis reveals fully human Omp38-specific monoclonal antibodies against Acinetobacter baumanniiBMC MicrobiolAugust 20, 2025Yiwei Zhang, Wenkang Yu, Peng Yu, Shufeng Wang, Hui Dong, Yong Qi, Xiaohua Chen, Li Zhang, Yuxiang Liu, Xing Mou, et al.washed three times. Serial dilutions of either recombinant mAb or isotype control mAb (MedChemExpress, HY-P99001) were added to the wells, and the plates were incubated at 37 ℃ for 1 h [22]. Following three washes,

(7) Chimeric Antigen Receptor T Cell with an Inducible Caspase 9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 TargetingClin Cancer ResAugust 1, 2024Marco Ventin, Giulia Cattaneo, Shahrzad Arya, Jingyu Jia, Maria Chiara Gelmi, Yi Sun, Luke Maggs, Bruce R. Ksander, Robert M. Verdijk, Genevieve M. Boland, et al.(enoblituzumab, MedChemExpress, catalog #HY-P9966, 10mg/kg/mouse) or human IgG1 kappa (MedChemExpress, catalog #HY-P99001, 10mg/kg/mouse) i.v. Enoblituzumab and the human IgG1 kappa isotype control were administered twice

(8) Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 TargetingClinical Cancer ResearchAugust 1, 2024Marco Ventin, Giulia Cattaneo, Shahrzad Arya, Jingyu Jia, Maria Chiara Gelmi, Yi Sun, Luke Maggs, Bruce R. Ksander, Robert M. Verdijk, Genevieve M. Boland, et al.(enoblituzumab, MedChemExpress, catalog #HY-P9966, 10mg/kg/mouse) or human IgG1 kappa (MedChemExpress, catalog #HY-P99001, 10mg/kg/mouse) i.v. Enoblituzumab and the human IgG1 kappa isotype control were administered twice

(9) KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLCCell death & diseaseFebruary 27, 2024Li J, Shi D, Li S, Shi X, Liu Y, Zhang Y, Wang G, Zhang C, Xia T, Piao HL, et al.Cycloheximide (#S7418, Selleck), anti-PD-L1 (#A2004, Selleck), Human IgG1 kappa, Isotype Control (#HY-P99001, MCE), purified GST-KEAP1 protein (#HY-P75899, MCE), purified PD-L1-Flag protein (#HY-P70663, MCE),

(10) Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B CellsCellJuly 9, 2020Cao Y, Su B, Guo X, Sun W, Deng Y, Bao L, Zhu Q, Zhang X, Zheng Y, Geng C, et al.

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Human IgG1 kappa, Isotype Control from MedChemExpress

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Human IgG1 kappa, Isotype Control from MedChemExpress

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