Human IgG4 (S228P) kappa, Isotype Control HY-P99003 from MedChemExpress

Product Specs
ItemHuman IgG4 (S228P) kappa, Isotype Control
CompanyMedChemExpress
Price $350.00Supplier Page View Company Product Page
Catalog NumberHY-P99003
Molecule NameHuman IgG4 kappa, Isotype Control
ApplicationsWB, ELISA, FA
Quantity1 mg
TypeChemical
Research AreaInflammation/Immunology

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(1) TGF-α/EGFR-mediated lymphatic metastasis reveals a repositionable therapeutic target in breast cancerNPJ Breast CancerApril 3, 2026Wenyang Shi, Yueyun Pan, Bhavik Rathod, Yuhan Wang, Zhi Wang, Jianyu Shen, Francesca Gatto, Mingzhi Liu, Yizhe Sun, Margareta Wilhelm, et al.single intravenous dose of Fepixnebart (10 mg/kg) or an isotype-matched human IgG4 control antibody (HY-P99003, MedChemExpress). On day 10 post-injection, inguinal (ILN) and axillary (ALN) lymph nodes were harvested,

(2) Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factorsNature CommunicationsDecember 20, 2025Vignesh Shanmugam, Neriman Tokcan, Daniel Chafamo, Sean Sullivan, Mehdi Borji, Haley Martin, Gail Newton, Naeem Nadaf, Saoirse Hanbury, Irving Barrera, et al.(MedChemExpress HY-P99025, lot: 594161). Human IgG4 Lambda (Millipore Sigma I4765-1MG) and Kappa (MedChemExpress HY-P99003) were used as isotype controls. Each therapeutic antibody or isotype control was serially diluted (500

(3) Dexamethasone drives macrophage repolarization linked to increased triple-negative breast cancer aggressivenessCell Death & DiseaseDecember 19, 2025Mohamed M. Shamekh, Birgitta Lindqvist, Ivan NalvarteFLT-1 neutralizing antibody Icrucumab (30 µg/ml, MedChemExpress; #HY-P99364, and control antibody #HY-P99003). In addition, primary CD14+ human peripheral blood monocytes (hPBMs) were purchased from PromoCell

(4) Targeting the HLA-E-NKG2A axis in combination with MS-275 enhances NK cell-based immunotherapy against DMGJ Exp Clin Cancer ResApril 29, 2025Yuxuan Deng, Jinqiu Liu, Zhuonan Pu, Yi Wang, Tian Li, Zhuang Jiang, Luyang Xie, Xiaoli Zhang, YingDan Chen, Mingxu Yang, et al.or without Monalizumab (50 μg, MCE, Cat# HY-P99032) or an isotype control antibody (50 μg, MCE, Cat# HY-P99003). The tumor burdens were monitored once a week by bioluminescence imaging using an IVIS Spectrum (PerkinElmer)

(5) The neonatal Fc receptor (FcRn) is a pan-arterivirus receptorNature communicationsAugust 7, 2024Shaw TM, Huey D, Mousa-Makky M, Compaleo J, Nennig K, Shah AP, Jiang F, Qiu X, Klipsic D, Rowland RRR, et al.media was removed and orilanolimab (Invitrogen, #MA5-42215) or IgG4,k isotype control (MedChemExpress, #HY-P99003) in serum free media was added. Cells were preincubated at 4 °C for 1 hr. After the initial incubation,

(6) Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuationLeukemiaJanuary 1, 2024Huuhtanen J, Adnan-Awad S, Theodoropoulos J, Forstén S, Warfvinge R, Dufva O, Bouhlal J, Dhapola P, Duàn H, Laajala E, et al.cytotoxicity assay Anti-TIM3 blocking antibody, sabatolimab (MCE, HY-P99044), or IgG4 kappa (MCE, HY-P99003) was added to expanded NK cells (20,000/well) on 96 well plate for 20 min on +37 °C. K562 or LAMA84

(7) Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cellGut microbesDecember 1, 2023Zhu X, Li K, Liu G, Wu R, Zhang Y, Wang S, Xu M, Lu L, Li P.96 U-shaped wells in the presence of anti-PD-1 treatment for another 6 h. Human IgG4 (10 μg/mL; MCE, HY-P99003) was used as the isotype control for anti-PD-1 treatment. Chromatin immunoprecipitation Vehicle- or

(8) Increased in vivo effector function of human IgG4 isotype antibodies through afucosylationmAbsAugust 1, 2016Gong Q, Hazen M, Marshall B, Crowell SR, Ou Q, Wong AW, Phung W, Vernes JM, Meng YG, Tejada M, et al.

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Human IgG4 (S228P) kappa, Isotype Control from MedChemExpress

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Human IgG4 (S228P) kappa, Isotype Control from MedChemExpress

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