Human Sortilin Antibody AF3154 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Sortilin Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF3154
NCBI Gene AliasesNT3, Gp95, LDLCQ6, NTR3
ApplicationsBioassay,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Blockade of Receptor-ligand Interaction,Neutralization,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
ReactivityHuman,Mouse,Primate,Transgenic Mouse
IsotypeIgG
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
TargetSortilin
NCBI Full Gene Namesortilin 1
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Sortilin, Ser78-Asn755, Accession # Q99523
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Putative long range mossy fiber sprouting and regional cytochrome c oxidase alteration in the hippocampus of patients with mesial temporal lobe epilepsyScientific ReportsJanuary 14, 2026Tian Tu, Lily Wan, Qi-Lei Zhang, Chen Yang, Hong-Shu Zhou, Zhong-Ping Sun, Hong-Yu Long, Bei-Sha Tang, Aihua Pan, Ewen Tu, et al.monoclonal anti-BACE1,Abcam,Cat# ab183612; RRID: AB_3094757 Goat polyclonal anti-Sortilin,R&D Systems,Cat# AF3154; RRID: AB_2286389 Mouse monoclonal anti-NeuN,Sigma-Aldrich,Cat# MAB377; RRID: AB_2298772 Rabbit polyclonal

(2) Increased expression of the proapoptotic presenilin associated protein is involved in neuronal tangle formation in human brainScientific reportsOctober 25, 2024Yang C, Sun ZP, Jiang J, Cai XL, Wang Y, Wang H, Che C, Tu E, Pan AH, Zhang Y, et al.AB_831049, Santa Cruz Biotechnology, Inc., Dallas, Texas, USA) and goat anti-sortilin (1:1000, Cat#AF3154, AB_2286389, R&D Systems, Inc., Minneapolis, MN, USA)30. Rabbit anti-Aβ (D12B2, 1:2000, Cat#50-204-9523,

(3) Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targetingFront Endocrinol (Lausanne)April 17, 2024Felix Bolduan, Alexandra Wetzel, Yvonne Giesecke, Ines Eichhorn, Natalia Alenina, Michael Bader, Thomas E. Willnow, Bertram Wiedenmann, Michael Sigalfurther washing steps, the tissue was incubated overnight at 4°C with anti-sortilin antibody (1:100, af3154, R&D systems). After repeated washing steps, tissue was incubated for 30 min at room temperature with

(4) Altered plasma protein profiles in genetic FTD - a GENFI studyMolecular neurodegenerationNovember 15, 2023Ullgren A, Öijerstedt L, Olofsson J, Bergström S, Remnestål J, van Swieten JC, Jiskoot LC, Seelaar H, Borroni B, Sanchez-Valle R, et al.from MBL International; MA1-70053, PA5-34943, 34–1000 from Invitrogen Antibodies; MAB2037-SP, AF2420, AF3154 from R&D Systems). The mean coefficient of variance per 384-well plate (n = 3) was less than 10%, and

(5) Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formationFrontiers in aging neuroscienceJanuary 1, 2022Jiang J, Yang C, Ai JQ, Zhang QL, Cai XL, Tu T, Wan L, Wang XS, Wang H, Pan A, et al.a.a.12–30),Polyclonal,Sheep,"1/2,500","1/1,000" Sortilin (CT),Abcam,ab16640,Polyclonal,Rabbit,"1/1,000",1/100 Sortilin (ECD),R&D Systems,AF3154,Polyclonal,Goat,"1/1,000",1/100 TOMM34,Santa Cruz,sc-101284,S-05,Mouse,"1/6,400","1/2,000" TOMM34,Protein

(6) Regional and Cellular Mapping of Sortilin Immunoreactivity in Adult Human BrainFrontiers in neuroanatomyJanuary 1, 2019Xu SY, Zhang QL, Zhang Q, Wan L, Jiang J, Tu T, Manavis J, Pan A, Cai Y, Yan XX.stained with the goat antibody raised against sortilin extracellular domain (diluted at 1:2000, Cat#AF3154, raised against recombinant Gly76 to Asn753 of human sortilin, R&D Systems China Co., Ltd., Shanghai,

(7) proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processingMolecular brainNovember 14, 2018Fleitas C, Piñol-Ripoll G, Marfull P, Rocandio D, Ferrer I, Rampon C, Egea J, Espinet C.

(8) Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by SortilinScientific reportsJune 13, 2018Hagita S, Rogers MA, Pham T, Wen JR, Mlynarchik AK, Aikawa M, Aikawa E.(Thermo Fisher Scientific). Human cell line Sortilin was detected using an anti-Sortilin antibody (R&D Systems #AF3154) and GAPDH (Santa Cruz, #sc-47724, Dallas, TX, USA) was used as a loading control. Adipose tissue protein

(9) Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaquesAlzheimer's research & therapyApril 24, 2018Zhou FQ, Jiang J, Griffith CM, Patrylo PR, Cai H, Chu Y, Yan XX.domain (diluted at 1:2000, catalog Zhou et al. Alzheimer's Research & Therapy (2018) 10:40 number AF3154, raised against recombinant Gly76 to Asn753 of human sortilin, catalog number 2934-ST, R&D Systems China

(10) Sortilin Fragments Deposit at Senile Plaques in Human CerebrumFrontiers in neuroanatomyJanuary 1, 2017Hu X, Hu ZL, Li Z, Ruan CS, Qiu WY, Pan A, Li CQ, Cai Y, Shen L, Chu Y, et al.immunohistochemically with four antibodies: goat anti-sortilin extracellular domain (diluted at 1:2000, AF3154, immunogenic peptide corresponding to amino acid (a.a.) 76–753 of human sortilin, AF3154-SP, R&D Systems

(11) Role of endogenous brain-derived neurotrophic factor and sortilin in B cell survivalJournal of immunology (Baltimore, Md. : 1950)September 1, 2008Fauchais AL, Lalloué F, Lise MC, Boumediene A, Preud'homme JL, Vidal E, Jauberteau MO.

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Human Sortilin Antibody

Sortilin Antibody

Sortilin Antibody

Sortilin Antibody

Sortilin Antibody

Human Sortilin Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Human Sortilin Antibody from R&D Systems, a Bio-Techne Brand

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