Infliximab HY-P9970 from MedChemExpress

Product Specs
ItemInfliximab
CompanyMedChemExpress
Price $132.00Supplier Page View Company Product Page
Catalog NumberHY-P9970
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Research AreaNeurological Disease; Metabolic Disease; Inflammation/Immunology; Cancer
TypeChemical
Quantity1 mg
Molecule NameInfliximab

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(1) Penfluridol Triggers GSDME-Mediated Immunogenic Pyroptosis to Potentiate Antitumor ImmunotherapyAdv Sci (Weinh)July 3, 2026Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, et al.necrostatin‐1s (HY‐14622A), Z‐VAD (HY‐16658B), Fer‐1 (HY‐100579), DL‐dithiothreitol (HY‐15917), Infliximab (HY‐P9970), Etanercept (HY‐108847) and Tetrathiomolybdate (HY‐128530) were purchased from MedChemExpress. All

(2) miR-941 in extracellular vesicles confers anlotinib resistance via Keap1/Nrf2 axis and represents a therapeutic target in non-small cell lung cancerClin Transl MedJune 15, 2026Aimi Huang, Xiaoqi Li, Erpeng Wu, Menglan Hao, Weimin Wang, Jinjing Xia(MCE, Cat#HY‐100523; specific Nrf2 inhibitor), the TNF‐α neutralizing antibody infliximab (MCE, Cat#HY‐P9970), and the pan‐caspase inhibitor Z‐VAD‐FMK (MCE, Cat#HY‐16658B, 20 µM, 24 h). 2.3 Extracellular vesicle

(3) TNF-α impairs the stria vascularis by inducing pericyte apoptosis via the NF-κB pathway in gentamicin-induced hearing lossJournal of NeuroinflammationMarch 28, 2026Gen Li, Guisheng Chen, Rui Hu, Junbo Zeng, Peiwen Liu, Maojin Liang, Yiqing ZhengReceived daily i.p. injections of gentamicin sulfate (150 mg/kg) for 14 days. Infliximab (MedChemExpress, HY-P9970) was prepared in sterile PBS at a concentration of 1 mg/ml before use. JSH-23 (MedChemExpress, HY-13982)

(4) Estrogen receptor 1 activation suppresses microglia-derived Tnf-α signaling as a photoreceptor self-protection mechanismJournal of neuroinflammationDecember 22, 2025Li Y, Li Y, Luo J, Wang L, Yang Q, Yang Q, Duan C, Xu W, Dong Y, Kong L, et al.MedChemExpress), 0.63 nM Etanercept [34] (ETN, HY-108847; MedChemExpress), 6.7 μM Infliximab [35] (IFX, HY-P9970; MedChemExpress), 65 μM R7050 [36] (HY-110203; MedChemExpress), or 4 μM AZD8797 [37] (HY-13848; MedChemExpress).

(5) TREM1 facilitates nonresponse to anti-TNF-α monoclonal antibodies in colitis via boosting ITCH/TAK1/caspase-8 axis-mediated macrophage pyroptosisJournal of Translational MedicineNovember 18, 2025Xiao-Man Liu, Zhen-Zhen Dai, Shang-Jian Luo, Jin-Yang Zhai, Yang Xie, Ying-Wei Chendextran sodium (DSS) in the drinking water for 5 days to establish an acute colitis model. IFX (10 µg/g, HY-P9970, MCE) or control human IgG1 antibody (10 µg/g, HY-P99001, MCE) was injected via the tail vein for treatment.

(6) The Glycolysis-HIF-1α axis induces IL-1β of macrophages in rheumatoid arthritisArthritis Research & TherapySeptember 26, 2025Yimeng Jia, Rongli Li, Linfang Huang, Xunyao Wu, Lidan Zhao, Huaxia Yang, Xin You, Yunyun Fei100ng/ml of Interleukin-1 receptor antagonist (IL-1RN, HY-P7029, MedChemExpress), 10 µg/ml of Infliximab (HY-P9970, MedChemExpress), or Lenzilumab (HY-P99207, MedChemExpress) for 24 h, respectively. Metabolic measurement HMDMs

(7) Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε‐Aminocaproic Acid and TriethylenetetramineELECTROPHORESISSeptember 23, 2025Joanne Baxter, Lori Fitton, Cari E S Sänger ‐ van de Griendcomponents was assessed by analysing 2 mAbs with pIs at the extremities of the range, Infliximab (pI 7.6, HY‐P9970 MedChemExpress) and Rituximab (pI 9.4, HY‐P9913 MedChemExpress). The mAbs were diluted to 1 mg/mL

(8) ANXA6 Overexpression Causes Abnormal Decidual Macrophage-Trophoblast Crosstalk in Recurrent Spontaneous AbortionInternational Journal of Biological SciencesAugust 11, 2025Xin Chen, Xue Yao Li, Xue Qin Ma, Yan Zhang, Qian Lin Song, Jing Yangμmol/L, HY-18738, MCE)]. For TNF-α receptor blockade, cells were treated with infliximab (10 μg/mL, HY-P9970, MCE)]. For activation of the PI3K signaling pathway, the PI3K activator 740 Y-P (50 μg/mL, HY-P0175,

(9) Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated PyroptosisJ Inflamm ResFebruary 19, 2025Yufen Tan, Yuanyuan Ye, Cuibi Huang, Jie Li, Lihua Huang, Xinyan Wei, Tong Liang, Enyuan Qin, Guolin Xiong, Yanfei BinShanghai, China). Recombinant TNF-α (RP01071) was obtained from ABclonal (Wuhan, China). Infliximab (HY-P9970), MCC950 (HY-12815A), and R-7050 (HY-110203) were obtained from MedChemExpress (NJ, USA). RNA-easy Isolation Reagent (R701

(10) Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated PyroptosisJ Inflamm ResFebruary 19, 2025Yufen Tan, Yuanyuan Ye, Cuibi Huang, Jie Li, Lihua Huang, Xinyan Wei, Tong Liang, Enyuan Qin, Guolin Xiong, Yanfei BinShanghai, China). Recombinant TNF-α (RP01071) was obtained from ABclonal (Wuhan, China). Infliximab (HY-P9970), MCC950 (HY-12815A), and R-7050 (HY-110203) were obtained from MedChemExpress (NJ, USA). RNA-easy Isolation Reagent (R701

(11) Cytokine and chemokine receptor profiles in adipose tissue vasculature unravel endothelial cell responses in HIVJournal of Cellular PhysiologyNovember 1, 2024Laventa M. Obare, Stephen Priest, Anas Ismail, Mona Mashayekhi, Xiuqi Zhang, Lindsey K. Stolze, Quanhu Sheng, Kisyua Nthenge, Zer Vue, Kit Neikirk, et al.up for the media and plasma conditions with the addition of 10ng/mL infliximab (MedChemExpress, MCE HY-P9970) at time 0. Cells were cultured for 24 hours before cell harvesting. We aspirated the supernatants and

(12) Human cytomegalovirus UL23 exploits PD-L1 inhibitory signaling pathway to evade T cell-mediated cytotoxicitymBioJuly 17, 2024Yuan Q, Fan Z, Huang W, Huo X, Yang X, Ran Y, Chen J, Li H.a concentration of 10 µg/mL, infliximab (MedChemExpress, Monmouth Junction, NJ, USA; catalog number HY-P9970) at a concentration of 10 ng/mL, anti-CD274 (PD-L1, B7-H1) antibody (10 µg/mL; eBioscience, San Diego,

(13) Co-administration of 1,25-dihydroxyvitamin D3 and infliximab improves colitis in mice by modulating Treg differentiationIranian journal of basic medical sciencesJanuary 1, 2024Hu Y, Wang Y, Chen Y, Li C, Long Y, Wu C.group (2 μg/kg, p.o, Catalog# D1530, Sigma‒Aldrich, St. Louis, MO, USA); (4-5) IFX group (Catalog# HY-P9970, MedChemExpress LLC, Shanghai, China, 2.5 mg/kg, 5.0 mg/kg, IP); (6) VitD3+ IFX group (2.5 mg/kg); (7)

(14) Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer's disease pathology in the 5xFAD mouseActa neuropathologica communicationsAugust 21, 2023Crivelli SM, Quadri Z, Vekaria HJ, Zhu Z, Tripathi P, Elsherbini A, Zhang L, Sullivan PG, Bieberich E.10 µM of Imipramine (Sigma-Aldrich, I7379) or 10 ng/mL of TNF-α receptor inhibitor (MedChemExpress, HY-P9970) or 10 µM of TLR4 Inhibitor (TAK-242), microglia were sonicated in ice-cold lysis buffer containing

(15) Single-cell RNA-seq analysis reveals that immune cells induce human nucleus pulposus ossification and degenerationFrontiers in immunologyJanuary 1, 2023Guo S, Yan M, Li X, Zhang S, Liu Z, Li K, Liu P, Liu Y, Sun G, Fu Q.group: AFP group) (11). For twelve rats, the TNF-α specific inhibitor (MedChemExpress, Infliximab: HY-P9970) were injected during the puncture process. After 4 weeks, all the rats were anesthetized for the further

(16) Infliximab ameliorates tumor necrosis factor-alpha-induced insulin resistance by attenuating PTP1B activation in 3T3L1 adipocytes in vitroScandinavian journal of immunologyNovember 1, 2018Méndez-García LA, Trejo-Millán F, Martínez-Reyes CP, Manjarrez-Reyna AN, Esquivel-Velázquez M, Melendez-Mier G, Islas-Andrade S, Rojas-Bernabé A, Kzhyshkowska J, Escobedo G.

(17) Inactivation of TNF-α ameliorates diabetic neuropathy in miceAmerican journal of physiology. Endocrinology and metabolismNovember 1, 2011Yamakawa I, Kojima H, Terashima T, Katagi M, Oi J, Urabe H, Sanada M, Kawai H, Chan L, Yasuda H, et al.

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Infliximab from MedChemExpress

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Infliximab from MedChemExpress

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