APP (C) Anti-Human Rabbit IgG Affinity Purify 18961 from IBL- America

Product Specs
ItemAPP (C) Anti-Human Rabbit IgG Affinity Purify
CompanyIBL- America
Price $596.00Supplier Page View Company Product Page
Catalog Number18961
ApplicationsWB, IP
Quantity100 ug
ReactivityHuman
HostRabbit
IsotypeIgG
Regulatory StatusFor research use only, not for use in diagnostic procedures
ClonalityPolyclonal
FormatLyophilized product from 1% BSA in PBS containing 0.05% NaN3
PurityPurified with antigen peptide
ImmunogenSynthetic peptide in portion of C-terminus of Human APP
StorageLyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C

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IBL- America

8201 Central Ave NE Suite P

Minneapolis, Minnesota 55432

United States

Phone: 888-523-1246
763-780-2988

Company Profile

Website: http://www.ibl-america.com/

(1) Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer's diseaseJournal of neuroinflammationFebruary 21, 2024Wang T, Sobue A, Watanabe S, Komine O, Saido TC, Saito T, Yamanaka K.(#10323, 1:200; IBL, Nagoya, Japan), mouse anti-ACTB (#a5441, 1:5000; Sigma), rabbit anti-human APP (C) (#18961, 1:5000; IBL, Nagoya, Japan), mouse anti-GFAP (#G3893, 1:250, Sigma), rabbit anti-p-STAT3(Tyr705) (#9145,

(2) APP and Bace1: Differential effect of cholesterol enrichment on processing and plasma membrane mobilityiScienceMay 19, 2023Claudia Capitini, Alessandra Bigi, Niccolò Parenti, Marco Emanuele, Niccolò Bianchi, Roberta Cascella, Cristina Cecchi, Laura Maggi, Francesco Annunziato, Francesco Saverio Pavone, et al.were: Anti-Human sAPPβ-WildType (IBL 18957), Anti-Human sAPPα (IBL 11088), Anti-Human APP (C) (IBL 18961) and Anti-alpha Tubulin antibody (Abcam ab7291) at the concentrations indicated by the manufacturer.

(3) Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer's DiseaseThe journal of prevention of Alzheimer's diseaseJanuary 1, 2021Ochiai T, Nagayama T, Matsui K, Amano K, Sano T, Wakabayashi T, Iwatsubo T.anti-PERK (3192, CST), anti-BiP (610978, BD biosciences), anti-CHOP (ab11419, Abcam), anti-Human APP (C) (18961, IBL), anti-ADAM10 (ab124695, Abcam), anti-BACE1 (5606, CST), anti-α-tubulin (DM1A, Merck), anti-LC3B

(4) EphA4 regulates Aβ production via BACE1 expression in neuronsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyDecember 1, 2020Tamura K, Chiu YW, Shiohara A, Hori Y, Tomita T.3/23 The following antibodies were purchased from commercial suppliers: anti-C- terminal domain of APP (#18961, Immuno-Biological Laboratories, Gunma, Japan, 1:1000 dilution), anti-C terminus of sAPPβ (#18957, Immuno-Biological Laboratories

(5) Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid β peptide using CRISPR/Cas9-based screening systemFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJune 1, 2020Chiu YW, Hori Y, Ebinuma I, Sato H, Hara N, Ikeuchi T, Tomita T.1:1000 dilution), anti-ADAM10 (ab1997, Abcam, Cambridge, UK, 1:1000 dilution) anti-C-terminally APP (#18961, Immuno-Biological Laboratories, Fujioka-Shi, Gunma, Japan, 1:1,000 dilution), anti-C-terminally sAPPβ

(6) Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model miceEMBO molecular medicineMarch 1, 2018Kidana K, Tatebe T, Ito K, Hara N, Kakita A, Saito T, Takatori S, Ouchi Y, Ikeuchi T, Makino M, et al.for immunoblotting (1:5, NeuroMab 75‐140), anti‐BACE1 BACE1c (1:1,000, IBL #18711), anti‐APP APPc (1:1,000, IBL 18961), anti‐nicastrin N1660 (1:1,000, Sigma‐Aldrich N1660), anti‐ADAM10 (a kind gift from Dr. Paul Saftig)

(7) Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement miceMolecular NeurodegenerationDecember 1, 2015Jin Hu, Chia-Chen Liu, Xiao-Fen Chen, Yun-wu Zhang, Huaxi Xu, Guojun BuFuji film Luminescent Image Analyzer (LAS4000). An antibody that recognizes the C-terminus of APP (18961, IBL-America) was used for detecting APP and its C-terminal fragments. Anti-β-actin (Sigma) was used

(8) An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's diseaseEMBO molecular medicineFebruary 1, 2015Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido TC, Nakano M, Yamaguchi Y, Hashimoto Y, Staufenbiel M, et al.anti-rab9 (5118) from Cell Signaling Technology; anti-APP C-term (recognizes C-terminal part of APP, 18961), anti-APP N-term (10D1), and anti-sAPPβ-sw (10321, clone 6A1) from Immuno-Biological Laboratories;

(9) Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretaseNature CommunicationsMay 1, 2014Kunihiko Kanatsu, Yuichi Morohashi, Mai Suzuki, Hiromasa Kuroda, Toshio Watanabe, Taisuke Tomita, Takeshi Iwatsubo1:1,000 dilution for western blot analyses, 1:400 dilution for immunocytochemical analysis), anti-APPc (#18961, Immuno-Biological Laboratories, 1:1,000), anti-human Ab speciﬁc antibody 82E1 (#10323, Immuno-Biological Laboratories

(10) BACE1 activity is modulated by cell-associated sphingosine-1-phosphateThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 4, 2011Takasugi N, Sasaki T, Suzuki K, Osawa S, Isshiki H, Hori Y, Shimada N, Higo T, Yokoshima S, Fukuyama T, et al.Immuno-Biological Laboratories), BACE1 (c) (catalog #18711; Immuno-Biological Laboratories), APP (c) (catalog #18961; ImmunoBiological Laboratories), anti-mouse/rat APP (597) (catalog #28055; Immuno-Biological Laboratories),

(11) Presenilin-2 Mutation Causes Early Amyloid Accumulation and Memory Impairment in a Transgenic Mouse Model of Alzheimer's DiseaseJournal of Biomedicine and BiotechnologyJanuary 1, 2011Toshihiko Toda, Yoshihiro Noda, Genzo Ito, Masahiro Maeda, Takahiko Shimizu(IBL, No. 18580), anti-Aβ(N); 1 : 2,000 (IBL, No. 10323, clone 82E1), anti-APP(C); 1 : 100 (IBL, No. 18961), anti-sAPPα; 1 : 20 (IBL, No. 11088, clone 2B3), anti-sAPPβ; 1 : 20 (IBL, No. 10321, clone 6A1) and

(12) A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's diseaseJournal of NeuroscienceAugust 18, 2010Hiroaki Fukumoto et al.medium from hybridoma), respectively, and polyclonal antibodies to the C terminus of APP [APP(C), No. 18961; IBL, 1:1000 dilution] that detect total APP and APP-CTFs, anti-mouse/rat APP [APP(597), No. 28055;

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APP (C) Anti-Human Rabbit IgG Affinity Purify from IBL- America

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IBL- America

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APP (C) Anti-Human Rabbit IgG Affinity Purify from IBL- America

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