Fig 1: Both 8.5 Gy RCI and SW alone significantly upregulate VEGF expression in skin wounds on day 30, and no significant differences are observed between sham and 9.0 Gy RCI (A). (B) There were no differences in serum VEGF levels in all groups. (C) Western blot analysis of CTGF expression in skin wounds, and their band densitometry analysis as shown in (D). CTGF (connective tissue growth factor) expression was upregulated in wound and RCI groups. * p < 0.05 for wound vs. sham, RCI 8.5 Gy vs. sham, and RCI 9.0 Gy vs. sham by Mann–Whitney Test (unpaired, two-tailed); N = 4. MW: molecular weight.