Bioss Inc.'s IKB beta Antibody is a Mouse monoclonal antibody. The IKB beta Antibody was generated using NFKB inhibitor beta, and NFKBIB as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: Western Blot.
Description
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation