Description
Product Characteristics:
Synonyms: FLJ90724, High temperature requirement protean A4, High-temperature requirement factor A4, HTRA 4, HtrA serine peptidase 4, HTRA4, HTRA4_HUMAN, Probable serine protease HTRA4, Serine protease HTRA4
Target Information: This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]