Description
Product Characteristics:
Synonyms: C20ORF1, C20orf2, Chromosome 20 Open Reading Frame 1, Dferentially expressed in cancerous and non-cancerous lung cells 2, Dferentially expressed in cancerous and noncancerous lung cells 2, Dferentially expressed in lung cells 2, Dferentially expressed in lung cells, DIL 2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA 519, HCA519, HCTP 4, HCTP4, Hepatocellular carcinoma associated antigen 519, Hepatocellular carcinoma-associated antigen 519, p100, Preferentially expressed in colorectal cancer, Protein FLS353, REPP 86, repp86, Restricted expression proliferation associated protein 100, Restricted expression proliferation-associated protein 100, Targeting protein for XKLP2, TPX 2, TPX2, TPX2 microtubule associated homolog, TPX2 microtubule associated protein homolog, TPX2_HUMAN.
Target Information: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity)