PD-1 (Intracellular Domain) (D4W2J) XP ® Rabbit mAb (PE Conjugate) from Cell Signaling Technology

Yes, the PD-1 (Intracellular Domain) (D4W2J) XP Rabbit mAb (PE Conjugate) has been shown to work effectively in flow cytometry applications specifically for human samples, as indicated by its reactivity with Homo sapiens.

Targeting the PDCD1 gene, which encodes the programmed cell death protein 1 (PD-1), is significant in immunology and cancer research. PD-1 plays a crucial role in regulating immune responses, and its modulation has implications for cancer therapies and understanding immune checkpoint pathways.

Yes, this antibody has been cited in at least one scientific article, indicating its application in research settings. This suggests that it has been validated for use in studies related to its target, PDCD1.

The PD-1 (Intracellular Domain) antibody is conjugated to an orange emitter, which emits light in the 560-589 nm range. This characteristic is beneficial for flow cytometry, as it allows for effective detection and analysis of PD-1 expression in human cells amidst other fluorescent markers.