MyBioSource.com's Rac1,2,3 Antibody is a Mouse monoclonal antibody. The Rac1,2,3 Antibody was generated using RAC2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
Rac is a subfamily of the Rho family of GTPases, small (~21 kDa) signaling G proteins (more specifically a GTPase). When bound to GTP, Rac is activated. In its activated state, Rac participates in the regulation of cell movement, through its involvement in structural changes to the actin Cytoskeleton. Rac is small GTPases that have been linked to multiple human cancers and are implicated in epithelial to mesenchymal transition, cell-cycle progression,migration/invasion, tumor growth, angiogenesis, and oncogenic transformation