The Anti-PRR7 Purified Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PRR7. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-PRR7 Purified Antibody has been shown to work in the following applications: Immunocytochemistry, and Western Blot.
Description
PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse