MyBioSource.com's Rabbit Anti-PGP9. 5/UchL1 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-PGP9. 5/UchL1 Antibody was generated using UCHL1 as the antigen. It reacts with Human, Rat, and Canine. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This MAb reacts with a protein of 20-30kDa, identified as PGP9. 5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9. 5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9. 5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9. 5 gene is believed to cause a form of Parkinson's disease