The Poliovirus Receptor/PVR Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PVR, and PVR cell adhesion molecule. This antibody recognizes Human antigen. The Poliovirus Receptor/PVR Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]