The Rabbit Anti-STAT5A Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to STAT5a. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-STAT5A Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. Activation of STAT5a induces dimerization, nuclear translocation and DNA binding. Stat5A is activated by IL-2, IL-7, IL-15, IL-3, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin; activation and dimerization of Stat5A requires phosphorylation of tyrosine 694