The Rabbit Anti-Arrestin 1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ARRB1, and Arrestin beta 1. This antibody recognizes Human antigen. The Rabbit Anti-Arrestin 1 Antibody has been shown to work in the following applications: Other.
Description
Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation