MyBioSource.com's Rabbit Anti-BETA-NGF Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The Rabbit Anti-BETA-NGF Antibody was generated using nerve growth factor, and NGF as the antigen and it reacts with Human.
Description
Rabbit anti Human beta-NGF antibody, recognizes beta-Nerve Growth Factor (beta-NGF), a member of the neurotrophin family of proteins. Beta-NGF plays a crucial role in neuronal cell survival and differentiation. It is also critical for the development and maintenance of the nervous system (Yue et al. 2013).
Beta-NGF elicits its biological function through the transmembrane recetprs trkA and p75NTR. Upon activation of these receptors by beta-NGF, a multitude of signaling pathways are stimulated including MAPK, PI3K and ERK, that sensitize neurons and stimulate growth of axons and dendrites (Huang et al. 2018)