The Complement C3 (beta-Chain) Antibody from MyBioSource.com is a Mouse Monoclonal antibody to C3, and complement C3. This antibody recognizes Human antigen. The Complement C3 (beta-Chain) Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, and Western Blot.
Description
Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates