The SCAI Antibody from MyBioSource.com is a Mouse Monoclonal antibody to SCAI. This antibody recognizes Human antigen. The SCAI Antibody has been shown to work in the following applications: Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Protein SCAI, also known as Suppressor of cancer cell invasion protein, and encoded by the gene name SCAI, is a tumor suppressor that suppresses MKL1-induced SRF transcriptional activity. It is a regulator of cell migration and appears to be involved in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. SCAI localizes in the nucleus, where it binds and inhibits the myocardin-related transcription factor MAL by forming a ternary complex with serum response factor (SRF)