The Histone H1.0 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H1-0, and H1.0 linker histone. This antibody recognizes Human, Mouse, and Rat antigen. The Histone H1.0 Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division