The SORD Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Sorbitol dehydrogenase, and SORD. This antibody recognizes Human, Mouse, and Rat antigen. The SORD Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor