The Rabbit Anti-Glucagon Receptor Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GCGR, and Glucagon Receptor. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Glucagon Receptor Antibody has been shown to work in the following applications: Immunofluorescence.
Description
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system