MyBioSource.com's Rabbit Anti-FAK Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The Rabbit Anti-FAK Antibody was generated using PTK2 as the antigen and it reacts with Human, and Rat.
Description
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity