The Rabbit Anti-AurB/C Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AURKC, and Aurora Kinase C. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-AurB/C Antibody has been shown to work in the following applications: Other.
Description
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'