COMP Polyclonal Antibody from MyBioSource.com

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COMP Polyclonal Antibody

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The COMP Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to COMP. This antibody recognizes Human, Mouse, and Rat antigen. The COMP Polyclonal Antibody has been shown to work in the following applications: Western Blot.

Description

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)