MyBioSource.com's SLC25A12 Rabbit mAb is a Rabbit monoclonal antibody. The SLC25A12 Rabbit mAb Antibody was generated using SLC25A12 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunoprecipitation, and Western Blot.
Description
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]
Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane (PubMed:11566871, PubMed:25410934). May have a function in the urea cycle (PubMed:11566871)