The TPX2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TPX2, and TPX2 microtubule nucleation factor. This antibody recognizes Human, and Mouse antigen. The TPX2 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation