MyBioSource.com's Rabbit Anti-Ephrin B1/B2/B3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The Rabbit Anti-Ephrin B1/B2/B3 Antibody was generated using EFNB1, and Ephrin B1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Cell surface transmembrane ligand for EpHreceptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously EpHreceptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). (Microbial infection) Acts as a receptor for nipah virus and hendra virus