MyBioSource.com's SynGAP Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Western Blot. The SynGAP Rabbit pAb Antibody was generated using SYNGAP1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of thenMDAR signaling complex in excitatory synapses, it may play a role innMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits