The Anti-Hu CD41b Purified Antibody from MyBioSource.com is a Mouse Monoclonal antibody to ITGA2B. This antibody recognizes Human, and Non-Human Primate antigen. The Anti-Hu CD41b Purified Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, and Immunohistochemistry - frozen.
Description
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation