The PLOD3 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PLOD3. This antibody recognizes Human, Mouse, and Rat antigen. The PLOD3 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity