The Anti-IDO-2/IDO2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to IDO2. This antibody recognizes Human, Mouse, Rat, and Non-Human Primate antigen. The Anti-IDO-2/IDO2 Antibody has been shown to work in the following applications: EIA, Immunoassay, Cell Sorting, Isolation, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
IDO2(Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by the INDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped on chromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11. 21. By database analysis using INDO as probe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan as determined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The Gene Structure of the INDOL1 has 11 exons and spans 74 kb