The Annexin-2/ANXA2 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Annexin A2, and ANXA2. This antibody recognizes Human, Mouse, and Rat antigen. The Annexin-2/ANXA2 Rabbit mAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]