The RASGRP1 Polyclonal Conjugated Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RasGRP1. This antibody recognizes Human antigen. The RASGRP1 Polyclonal Conjugated Antibody has been shown to work in the following applications: Other.
Description
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE)