The Rabbit Anti-DNA Replication Licensing Factor MCM2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MCM2. This antibody recognizes Human antigen. The Rabbit Anti-DNA Replication Licensing Factor MCM2 Antibody has been shown to work in the following applications: Other.
Description
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \'once per cell cycle\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division