The Rabbit Anti-PD-L1/PDCD1LG1/CD274/B7-H1 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to CD274. This antibody recognizes Human antigen. The Rabbit Anti-PD-L1/PDCD1LG1/CD274/B7-H1 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system