MyBioSource.com's PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2) Antibody is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin family. CD49d is also known as integrin alpha4 (ITGA4). Together with integrin beta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin beta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1