The EBP1 (Center) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PA2G4. This antibody recognizes Human, and Mouse antigen. The EBP1 (Center) Rabbit pAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity)