MyBioSource.com's MRGPRX1 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The MRGPRX1 Rabbit pAb Antibody was generated using MRGPRX1 as the antigen and it reacts with Mouse, and Rat.
Description
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner