Anti-Hu CD102 PE from MyBioSource.com

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Anti-Hu CD102 PE

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MyBioSource.com's Anti-Hu CD102 PE is a Mouse monoclonal antibody. The Anti-Hu CD102 PE Antibody was generated using Icam2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.

Description

CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration