The TDP1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TDP1. This antibody recognizes Human antigen. The TDP1 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence.
Description
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1)