MyBioSource.com's PDK2 Mouse mAb is a Mouse monoclonal antibody. The PDK2 Mouse mAb Antibody was generated using PDK2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene