The IMPDH2 Conjugated Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to IMPDH2. This antibody recognizes Human, Mouse, and Rat antigen. The IMPDH2 Conjugated Antibody has been shown to work in the following applications: Other.
Description
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation