MyBioSource.com's GDNF Receptor alpha 2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, and Immunofluorescence. The GDNF Receptor alpha 2 Antibody was generated using GFRA2 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
Subcellular Location: Cell membrane>Lipid-anchor.
Tissue Specificity: Isoform 1 is found in both brain and placenta.
Subunit Structure: Interacts with SORL1.
Similarity: Belongs to the GDNFR family