The Anti-Ms CD49e Purified Antibody from MyBioSource.com is a Rat Monoclonal antibody to ITGA5. This antibody recognizes Mouse antigen. The Anti-Ms CD49e Purified Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, and Immunohistochemistry - frozen.
Description
CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis